Abnova/抗TARDBP单克隆抗体/1kit/DH0016
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Anti-TARDBP is intended for the semi-quantitative detection of TAR DNA Binding Protein (TARDBP ) in paraffin sections.
- Immunogen:
- TARDBP (NP_031401.1, 1 a.a. ~ 260 a.a) recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human TAR DNA binding protein
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (TAR去氧核糖核酸結合酶-43單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (S1)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TARDBP on formalin-fixed paraffin-embedded human lung. [antibody concentration 0.75 ug/ml]
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TARDBP on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.75 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 23435
- Gene Name:
- TARDBP
- Gene Alias:
- ALS10,TDP-43
- Gene Description:
- TAR DNA binding protein
- Omim ID:
- 605078
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002171,TAR DNA-binding protein-43
- Related Disease
- Alzheimer Disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Chromosome Disorders
- Dementia
- Genetic Predisposition to Disease
- Neurodegenerative Diseases
- Parkinson Disease
- Parkinson disease
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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