Abnova/抗HSD3B1单克隆抗体/1kit/DH0007
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Anti-HSD3B1 is intended for the semi-quantitative detection of Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta-And Steroid Delta-Isomerase 1 (HSD3B1) in paraffin sections.
- Immunogen:
- HSD3B1 (AAH31999.1, 1 a.a. ~373 a.a.) full length recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (羥基-δ-5-類固醇脫氫酶-3β-和類固醇δ異構酶1單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (3C11-D4)
- Publication Reference
- 1.
- Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions.Azmahani A, Nakamura Y, Felizola SJ, Ozawa Y, Ise K, Inoue T, McNamara KM, Doi M, Okamura H, Zouboulis CC, Aiba S, Sasano H.J Steroid Biochem Mol Biol. 2014 Jul 29. pii: S0960-0760(14)00134-4. doi: 10.1016/j.jsbmb.2014.07.010.
- 2.
- Gestational Trophoblastic Tumors and Related Tumor-Like Lesions.Shih IM, Mazur MT, Kurman RJ.Blaustein"s Pathology of the Female Genital Tract 2011, 1075-1135, DOI: 10.1007/978 -1-4419-0489-8_20
- 3.
- Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions.Mao TL, Shih IM.Expert Opin. Med. Diagn. (2009) 3(4):371-380
- 4.
- Chorangiocarcinoma: A Case Report and Review of the Literature.Ariel I, Boldes R, Weintraub A, Reinus C, Beller U, Arbel R.Int J Gynecol Pathol. 2009 May;28(3):267-71.
- 5.
- HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions.Mao TL, Kurman RJ, Jeng YM, Huang W, Shih IM.Am J Surg Pathol. 2008 Feb;32(2):236-42.
- 6.
- Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions.Shih IeM.Ann Diagn Pathol. 2007 Jun;11(3):228-34.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to HSD3B1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 0.02344 ug/ml]
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunohistochemical staining of various tissues with hematoxylin and HSD3B1 antibody under high magnification. [antibody concentration 3 ug/ml]( a ) Stomach( b ) Esophagus( c ) Endometrium( d ) Uterine cervix( e ) Placenta( f ) Ovary, clear cell carcinoma( g ) Hepatocellular carcinoma( h ) Breast cancer( i ) Colon adenocarcinoma ( j and k ) Cervical carcinoma( l, m, and n ) Choriocarcinoma( o ) Epithelioid trophoblastic tumor
- Protocol Download
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 3283
- Gene Name:
- HSD3B1
- Gene Alias:
- HSD3B,HSDB3,SDR11E1
- Gene Description:
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Omim ID:
- 109715
- Gene Ontology:
- Hyperlink
- Other Designations:
- hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1,short chain dehydrogenase/reductase family 11E, member 1
- Gene Pathway
- Androgen and estrogen metabolism
- C21-Steroid hormone metabolism
- Metabolic pathways
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hypertension
- Hypertrophy, Left Ventricular
- Infant, Premature, Diseases
- Kidney Failure, Chronic
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Neoplasms, Hormone-Dependent
- Obesity
- Obesity
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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