Abnova/Anti-GBA monoclonal antibody/1kit/DH0011
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Anti-GBA is intended for the semi-quantitative detection of Glucosidase, Beta, Acid (GBA ) in paraffin sections.
- Immunogen:
- GBA (NP_000148.2, 146 a.a. ~ 235 a.a) recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human Glucosidase, beta, acid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (酸性β葡萄糖苷酶單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (2E2)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to GBA on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to GBA on formalin-fixed paraffin-embedded human ovary cancer. [antibody concentration 3 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 2629
- Gene Name:
- GBA
- Gene Alias:
- GBA1,GCB,GLUC
- Gene Description:
- glucosidase, beta; acid (includes glucosylceramidase)
- Omim ID:
- 230800, 230900, 231000, 231005, 606463, 608013
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
- Other Designations:
- D-glucosyl-N-acylsphingosine glucohydrolase,OTTHUMP00000033992,OTTHUMP00000033993,glucocerebrosidase,glucocerebrosidase (alt.),lysosomal glucocerebrosidase
- Gene Pathway
- Lysosome
- Metabolic pathways
- Other glycan degradation
- Sphingolipid metabolism
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bone Diseases, Metabolic
- Cardiovascular Diseases
- Cognition Disorders
- Cystic fibrosis
- Deafness
- Dementia
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Epilepsy
- Essential Tremor
- Essential tremor
- Gaucher Disease
- Gaucher disease
- Genetic Diseases, Inborn
- Genetic Predisposition to Disease
- Hypergammaglobulinemia
品牌介绍
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