Abnova/抗CLDN1单克隆抗体/1kit/DH0015
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¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Anti-CLDN1 is intended for the semi-quantitative detection of Claudin 1 (CLDN1 ) in paraffin sections.
- Immunogen:
- CLDN1 (AAH12471.1, 1 a.a. ~ 211 a.a) recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human Claudin 1
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (緊密連接蛋白1單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (S4)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to CLDN1 on formalin-fixed paraffin-embedded human colon cancer. [antibody concentration 3 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 9076
- Gene Name:
- CLDN1
- Gene Alias:
- CLD1,ILVASC,SEMP1
- Gene Description:
- claudin 1
- Omim ID:
- 603718, 607626
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
- Other Designations:
- senescence-associated epithelial membrane protein 1
- Gene Pathway
- Cell adhesion molecules (CAMs)
- Leukocyte transendothelial migration
- Pathogenic Escherichia coli infection - EHEC
- Tight junction
- Related Disease
- Genetic Predisposition to Disease
- Hepatitis C
- Substance Abuse, Intravenous
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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