Abnova/CD45单克隆抗体（Alexa 647）/1kit/DH0072
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Alexa 647 conjugated mouse CD45 monoclonal antibody.
- Immunogen:
- Human peripheral blood leucocytes
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Conjugation:
- Alexa 647
- Concentration:
- 0.5 mg/mL
- Isotype:
- IgG1, kappa
- Quality Control Testing:
- ResultsSandwich ELISA
Sandwich ELISA performed with CD45 recombinant protein and CD45 monoclonal antibody (Alexa 647)Immunofluorescence
Immunofluorescence staining performed on Jurkat cells using CD45 monoclonal antibody (Alexa 647) (10 ug/mL).
- Recommend Usage:
- Immunofluorescence (10 ug/mL)LiquidCell™ SuperSlide™ (1.5 uL per slide)
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at 2-8°C. Do not freeze.
- Protocol:
Protocol Download
- Amenable Platform:
- LiquidCell™ negative enrichment cell isolation
- Available Test:
- 16 assays
- Regulatory Status:
- GMP grade
- Instrument Compatibility:
- Ventana™ BenchMark Stainer
- Datasheet:
- Download
- Applications
- Immunofluorescence
- Immunofluorescence staining performed on WBCs recoverd by SuperSlide™. CD45 was detected via red signal (Alexa 647).
- Application Image
- Immunofluorescence
- enlarge
- Gene Information
- Entrez GeneID:
- 5788
- Gene Name:
- PTPRC
- Gene Alias:
- B220,CD45,CD45R,GP180,LCA,LY5,T200
- Gene Description:
- protein tyrosine phosphatase, receptor type, C
- Omim ID:
- 126200, 151460, 609532
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
- Other Designations:
- CD45 antigen,T200 glycoprotein,T200 leukocyte common antigen,glycoprotein,leukocyte-common antigen,protein tyrosine phosphatase, receptor type, c polypeptide
- Gene Pathway
- Cell adhesion molecules (CAMs)
- Fc gamma R-mediated phagocytosis
- Primary immunodeficiency
- T cell receptor signaling pathway
- Related Disease
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Ascariasis
- Autoimmune Diseases
- Cardiomyopathy, Dilated
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Graves Disease
- Hashimoto Disease
- Hepatitis B
- Hepatitis C
- Hepatitis, Autoimmune
- HIV Infections
- Inflammatory Bowel Diseases
- Lupus Erythematosus, Systemic
- Lymphopenia
- Multiple Sclerosis
- Paraparesis, Tropical Spastic
- Scleroderma, Systemic
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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