Abnova/CASP3 MaxPab rabbit polyclonal antibody (D01)/1kit/H00000836-D01
商品编号：
H00000836-D01
品牌：
abnovadx
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human CASP3 protein.
- Immunogen:
- CASP3 (AAH16926.1, 1 a.a. ~ 277 a.a) full-length human protein.
- Sequence:
- MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Datasheet:
- Download
- Applications
- Western Blot (Tissue lysate)
- CASP3 MaxPab rabbit polyclonal antibody. Western Blot analysis of CASP3 expression in mouse liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of CASP3 expression in transfected 293T cell line (H00000836-T01) by CASP3 MaxPab polyclonal antibody.Lane 1: CASP3 transfected lysate(31.60 KDa).Lane 2: Non-transfected lysate.
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to CASP3 on HeLa cell. [antibody concentration 30 ug/ml]
- Immunoprecipitation
- Immunoprecipitation of CASP3 transfected lysate using anti-CASP3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CASP3 MaxPab rabbit polyclonal antibody (D01) (H00000836-D01).
- Protocol Download
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Western Blot (Transfected lysate)
- enlarge
- Immunofluorescence
- enlarge
- Immunoprecipitation
- enlarge
- Gene Information
- Entrez GeneID:
- 836
- GeneBank Accession#:
- NM_004346
- Protein Accession#:
- AAH16926.1
- Gene Name:
- CASP3
- Gene Alias:
- CPP32,CPP32B,SCA-1
- Gene Description:
- caspase 3, apoptosis-related cysteine peptidase
- Omim ID:
- 600636
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer"s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq
- Other Designations:
- OTTHUMP00000165054,PARP cleavage protease,SREBP cleavage activity 1,Yama,apopain,caspase 3,caspase 3, apoptosis-related cysteine protease,cysteine protease CPP32,procaspase3
- Interactome
- Gene Pathway
- Alzheimer"s disease
- Amyotrophic lateral sclerosis (ALS)
- Apoptosis
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- Huntington"s disease
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- p53 signaling pathway
- Parkinson"s disease
- Pathways in cancer
- Related Disease
- Adenocarcinoma
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Clubfoot
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Endometrial Neoplasms
- Esophageal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
品牌介绍
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