Abnova/ABCG8纯化MaxPab小鼠多克隆抗体（B01P）/1kit/H00064241-B01P
商品编号：
H00064241-B01P
品牌：
abnovadx
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human ABCG8 protein.
- Immunogen:
- ABCG8 (ADR83246.1, 1 a.a. ~ 673 a.a) full-length human protein.
- Sequence:
- MAGKAAEERGLPKGATPQHTSGLQDRLFSSESDNSLYFTYSGQPNTLEVRDLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWTVPAWISKVSFLRWCFEGLMKIQFSRRTYKMPLGNLTIAVSGDKILSAMELDSYPLYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Interspecies Antigen Sequence:
- Mouse (81); Rat (79)
- Datasheet:
- Download
- Applications
- Western Blot (Transfected lysate)
- Protocol Download
- Application Image
- Western Blot (Transfected lysate)
- Gene Information
- Entrez GeneID:
- 64241
- GeneBank Accession#:
- HQ258492.1
- Protein Accession#:
- ADR83246.1
- Gene Name:
- ABCG8
- Gene Alias:
- GBD4,MGC142217,STSL
- Gene Description:
- ATP-binding cassette, sub-family G (WHITE), member 8
- Omim ID:
- 210250, 605460
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
- Other Designations:
- ATP-binding cassette sub-family G member 8,ATP-binding cassette, subfamily G, member 8,sterolin 2
- Gene Pathway
- ABC transporters
- Related Disease
- Atherosclerosis
- Atherosclerosis
- Biliary Tract Neoplasms
- Cardiovascular Diseases
- Cholelithiasis
- Coronary Artery Disease
- Coronary Disease
- Diseases in Twins
- Dyslipidemias
- Gallbladder Neoplasms
- Gallstones
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Hyperlipidemias
- Hyperlipoproteinemia Type II
- Insulin Resistance
- Kidney Failure, Chronic
- Lung Neoplasms
- Metabolic Syndrome X
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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