Abnova/CD274多克隆抗体/1kit/PAB12985
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆基因
公司分类：
Cloned_Genes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CD274.
- Immunogen:
- A synthetic peptide corresponding to internal region 17 amino acids of human CD274.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Has no cross-reactivity to CD273.
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Isotype:
- IgG
- Recommend Usage:
- Flow Cytometry (0.5 ug/mL)Immunofluorescence (20 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL)Western Blot (0.5-1 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.02% sodium azide).
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Publication Reference
- 1.
- Hepatic Artery Embolization Enhances Expression of Programmed Cell Death 1 Ligand 1 in an Orthotopic Rat Hepatocellular Carcinoma Model: In Vivo and in Vitro Experimentation.Haruyuki Takaki, Yutaka Hirata, Eisuke Ueshima, Hiroshi Kodama, Seiji Matsumoto, Reona Wada, Hitomi Suzuki, Keiji Nakasho, Koichiro Yamakado.J Vasc Interv Radiol. 2020 Sep;31(9):1475-1482.e2. doi: 10.1016/j.jvir.2020.03.023. Epub 2020 Aug 14.
- 2.
- Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1).LaGier AJ, Pober JS.Hum Immunol. 2006 Aug;67(8):568-78. Epub 2006 May 19.
- 3.
- Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.Holling TM, Schooten E, van Den Elsen PJ.Hum Immunol. 2004 Apr;65(4):282-90.
- 4.
- Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.Ishida Y, Agata Y, Shibahara K, Honjo T.EMBO J. 1992 Nov;11(11):3887-95.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of CD274 in Raji cell lysate with CD274 polyclonal antibody (Cat # PAB12985) at (A) 0.5 and (B) 1 ug/mL .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry of CD274 in human heart tissue with CD274 polyclonal antibody (Cat # PAB12985) at 2.5 ug/mL .
- Immunofluorescence
- Immunofluorescence staining of human heart cells with CD274 polyclonal antibody (Cat# PAB12985) under 20 ug/mL working concentration.
- Enzyme-linked Immunoabsorbent Assay
- Flow Cytometry
- Flow cytometric analysis of A-20 cells with CD274 polyclonal antibody (Cat# PAB12985). Green: Isotype control. Red : CD274 antibody.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunofluorescence
- enlarge
- Enzyme-linked Immunoabsorbent Assay
- Flow Cytometry
- enlarge
- Gene Information
- Entrez GeneID:
- 29126
- Protein Accession#:
- NP_054862
- Gene Name:
- CD274
- Gene Alias:
- B7-H,B7H1,MGC142294,MGC142296,PD-L1,PDCD1L1,PDCD1LG1,PDL1
- Gene Description:
- CD274 molecule
- Omim ID:
- 605402
- Gene Ontology:
- Hyperlink
- Other Designations:
- CD274 antigen,OTTHUMP00000021029,programmed cell death 1 ligand 1
- Gene Pathway
- Cell adhesion molecules (CAMs)
- Related Disease
- Addison Disease
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Graves Disease
- Lupus Erythematosus, Systemic
- Multiple Sclerosis
- Narcolepsy
- Rheumatoid Nodule
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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