Abnova/CD244多克隆抗体/1kit/PAB19379
市场价：
¥0.00
美元价：
0.00
产品分类：
转录表达
公司分类：
Target_Expression
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CD244.
- Immunogen:
- A synthetic peptide corresponding to 16 amino acids near C-terminus of human CD244.
- Sequence:
- PKAQNPARLSRKELEN
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- At least three isoforms of CD244 are known to exist. This antibody is predicted to not cross-react with other SLAM protein family members.
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Concentration:
- 1 mg/mL
- Recommend Usage:
- Western Blot (1-2 ug/mL)Immunofluorescence (20 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of CD244 in Daudi cell lysate with CD244 polyclonal antibody (Cat # PAB19379) at (1) 1 and (2) 2 ug/mL.
- Immunofluorescence
- Immunofluorescencent staining of Daudi cells with CD244 polyclonal antibody (Cat # PAB19379) at 20 ug/mL.
- Enzyme-linked Immunoabsorbent Assay
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunofluorescence
- enlarge
- Enzyme-linked Immunoabsorbent Assay
- Gene Information
- Entrez GeneID:
- 51744
- Protein Accession#:
- NP_1160135
- Gene Name:
- CD244
- Gene Alias:
- 2B4,NAIL,NKR2B4,Nmrk,SLAMF4
- Gene Description:
- CD244 molecule, natural killer cell receptor 2B4
- Omim ID:
- 605554
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM
- Other Designations:
- CD244 natural killer cell receptor 2B4,NK cell activation inducing ligand NAIL,OTTHUMP00000027884,natural killer cell receptor 2B4
- Gene Pathway
- Natural killer cell mediated cytotoxicity
- Related Disease
- Arthritis, Rheumatoid
- Cell Transformation, Neoplastic
- Genetic Predisposition to Disease
- Lupus Erythematosus, Systemic
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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