Abnova/CASP3 p12单克隆抗体，克隆GEA-3/1kit/MAB19700
市场价：
¥0.00
美元价：
0.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against synthetic peptide of human CASP3 p12.
- Immunogen:
- A synthetic peptide corresponding to human CASP3 p12.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 31.608
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Affinity purification
- Isotype:
- IgG
- Recommend Usage:
- Immunocytochemistry (1:50-1:200)Immunofluorescence (1:50-1:200)Immunohistochemistry (1:100-1:500)ImmunoprecipitationWestern Blot (1:500-1:1000)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
- Storage Instruction:
- Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western Blot analysis of HeLa cell lysate with CASP3 p12 monoclonal antibody, clone GEA-3 (Cat # MAB19700).
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence
- Immunoprecipitation
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence
- Immunoprecipitation
- Gene Information
- Entrez GeneID:
- 836
- Protein Accession#:
- P42574
- Gene Name:
- CASP3
- Gene Alias:
- CPP32,CPP32B,SCA-1
- Gene Description:
- caspase 3, apoptosis-related cysteine peptidase
- Omim ID:
- 600636
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer"s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq
- Other Designations:
- OTTHUMP00000165054,PARP cleavage protease,SREBP cleavage activity 1,Yama,apopain,caspase 3,caspase 3, apoptosis-related cysteine protease,cysteine protease CPP32,procaspase3
- Interactome
- Gene Pathway
- Alzheimer"s disease
- Amyotrophic lateral sclerosis (ALS)
- Apoptosis
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- Huntington"s disease
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- p53 signaling pathway
- Parkinson"s disease
- Pathways in cancer
- Related Disease
- Adenocarcinoma
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Clubfoot
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Endometrial Neoplasms
- Esophageal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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