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Abnova/CD45RA monoclonal antibody, clone HI100 (PerCP)/1kit/MAB13678
Abnova/CD45RA monoclonal antibody, clone HI100 (PerCP)/1kit/MAB13678
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆试剂盒
公司分类：
Cloning_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against human CD45RA.
- Immunogen:
- Fresh human lymph node lymphocytes depleted of surface immunoglobulin positive cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 220
- Reactivity:
- Human
- Form:
- Liquid
- Conjugation:
- PerCP
- Purification:
- Protein A/G purification
- Purity:
- >90%
- Isotype:
- IgG2b, kappa
- Recommend Usage:
- Flow Cytometry (20 uL/106 cells)ImmunofluorescenceImmunohistochemistry (Frozen sections)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
- Storage Instruction:
- Store in the dark at 4°C.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- Flow Cytometry
- Flow cytometric analysis of human peripheral blood with CD45RA monoclonal antibody, clone HI100 (PerCP) (Cat # MAB13678).
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- Flow Cytometry
- enlarge
- Gene Information
- Entrez GeneID:
- 5788
- Protein Accession#:
- P08575
- Gene Name:
- PTPRC
- Gene Alias:
- B220,CD45,CD45R,GP180,LCA,LY5,T200
- Gene Description:
- protein tyrosine phosphatase, receptor type, C
- Omim ID:
- 126200, 151460, 609532
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
- Other Designations:
- CD45 antigen,T200 glycoprotein,T200 leukocyte common antigen,glycoprotein,leukocyte-common antigen,protein tyrosine phosphatase, receptor type, c polypeptide
- Gene Pathway
- Cell adhesion molecules (CAMs)
- Fc gamma R-mediated phagocytosis
- Primary immunodeficiency
- T cell receptor signaling pathway
- Related Disease
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Ascariasis
- Autoimmune Diseases
- Cardiomyopathy, Dilated
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Graves Disease
- Hashimoto Disease
- Hepatitis B
- Hepatitis C
- Hepatitis, Autoimmune
- HIV Infections
- Inflammatory Bowel Diseases
- Lupus Erythematosus, Systemic
- Lymphopenia
- Multiple Sclerosis
- Paraparesis, Tropical Spastic
- Scleroderma, Systemic
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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