Abnova/CD36单克隆抗体，克隆FA6.152/1kit/MAB4662
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆基因
公司分类：
Cloned_Genes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD36.
- Immunogen:
- Native purified CD36 from human fetal red blood cells.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- The molecular weight of the recognized antigen is 90KDa. Recognizes the glycoprotein gp lllb corresponding to the thrombospondin receptor. This antibody agglutinates fetal but not adult erythrocytes. It does not react with lymphocytes and granulocytes. It reacts both with fetal and adult monocytes, megakaryocytes, platelets and reticulocytes. The thrombospondin receptor is a very early marker of erythroid differentiation.
- Form:
- Lyophilized
- Isotype:
- IgG1
- Recommend Usage:
- Immunofluorescence (2ug/5x105 cells)Flow Cytometry (2ug/5x105 cells)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from PBS (1mg/mL BSA)
- Storage Instruction:
- Store at 4°C on dry atmosphere.After reconstitution with deionized water, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.
- Datasheet:
Download
- Publication Reference
- 1.
- Application of lyophilised human platelets for antibody detection in solid phase red cell adherence assay.Shengbao Duan, Mingyuan Wang, Shaohua Ding, Yezhou Chen, Shuangshi Wei, Wei Chen, Chun Zhang, Yong Li, Hongmei Wang.J Immunol Methods. 2020 Sep 15;112868. doi: 10.1016/j.jim.2020.112868. Online ahead of print.
- 2.
- A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors.Edelman P, Vinci G, Villeval JL, Vainchenker W, Henri A, Miglierina R, Rouger P, Reviron J, Breton-Gorius J, Sureau C, et al..Blood. 1986 Jan;67(1):56-63.
- Applications
- Immunohistochemistry
- Immunofluorescence
- Flow Cytometry
- Application Image
- Immunohistochemistry
- Immunofluorescence
- Flow Cytometry
- Gene Information
- Entrez GeneID:
- 948
- Gene Name:
- CD36
- Gene Alias:
- CHDS7,FAT,GP3B,GP4,GPIV,PASIV,SCARB3
- Gene Description:
- CD36 molecule (thrombospondin receptor)
- Omim ID:
- 173510, 248310, 608404, 610938, 611162
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- CD36 antigen,CD36 antigen (collagen type I receptor, thrombospondin receptor),PAS-4 protein,cluster determinant 36,fatty acid translocase,glycoprotein IIIb,leukocyte differentiation antigen CD36,platelet glycoprotein IV,scavenger receptor class B, member
- Gene Pathway
- Adipocytokine signaling pathway
- ECM-receptor interaction
- Hematopoietic cell lineage
- PPAR signaling pathway
- Related Disease
- Anemia
- Angina Pectoris
- Atherosclerosis
- Atherosclerosis
- Calcinosis
- Cardiovascular Diseases
- Colon cancer
- Colorectal Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Hepatitis, Toxic
- Hypertension
- Insulin Resistance
- Kidney Failure, Chronic
- Macular Degeneration
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
联络我们
