Abnova/ABCG2 monoclonal antibody, clone AODG-1/1kit/MAB19516
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆基因
公司分类：
Cloned_Genes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against synthetic peptide of human ABCG2.
- Immunogen:
- A synthetic peptide corresponding to human ABCG2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Affinity purification
- Isotype:
- IgG
- Recommend Usage:
- Western Blot (1:500-1:2000)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage Instruction:
- Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of 293T cell lysate with ABCG2 monoclonal antibody.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Gene Information
- Entrez GeneID:
- 9429
- Protein Accession#:
- Q9UNQ0
- Gene Name:
- ABCG2
- Gene Alias:
- ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1
- Gene Description:
- ATP-binding cassette, sub-family G (WHITE), member 2
- Omim ID:
- 603756
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
- Other Designations:
- ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
- Gene Pathway
- ABC transporters
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Colon cancer
- Colorectal Neoplasms
- Coronary Artery Disease
- Coronary Disease
- Crohn"s disease
- Diabetes Complications
- Diabetes Mellitus, Type 2
品牌介绍
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