Abnova/ABCG2单克隆抗体，克隆3G8/1kit/MAB10478
市场价：
¥0.00
美元价：
0.00
产品分类：
双杂交系统
公司分类：
Two_Hybrid_Systems
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant ABCG2.
- Immunogen:
- Recombinant protein corresponding to human ABCG2.
- Host:
- Mouse
- Theoretical MW (kDa):
- 72
- Reactivity:
- Human, Monkey, Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Recommend Usage:
- ELISA (1:10000)Western Blot (1:500-1:2000)Immunohistochemistry (1:200-1:1000)Immunofluorescence (1:200-1:1000)Flow cytometry (1:200-1:400)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) against NIH/3T3 (1) and COS-7 (2) cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues (A) and skeletal muscle tissues (B) using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) with DAB staining.
- Immunofluorescence
- Immunofluorescence analysis of HeLa cells using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
- Enzyme-linked Immunoabsorbent Assay
- ELISA detection with ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478).
- Flow Cytometry
- Flow cytometric analysis of HepG2 cells using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) (green) and negative control (purple).
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunofluorescence
- enlarge
- Enzyme-linked Immunoabsorbent Assay
- enlarge
- Flow Cytometry
- enlarge
- Gene Information
- Entrez GeneID:
- 9429
- Gene Name:
- ABCG2
- Gene Alias:
- ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1
- Gene Description:
- ATP-binding cassette, sub-family G (WHITE), member 2
- Omim ID:
- 603756
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
- Other Designations:
- ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
- Gene Pathway
- ABC transporters
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Colon cancer
- Colorectal Neoplasms
- Coronary Artery Disease
- Coronary Disease
- Crohn"s disease
- Diabetes Complications
- Diabetes Mellitus, Type 2
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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