Abnova/ALPL FISH探头/1kit/FA0022
市场价：
¥0.00
美元价：
0.00
产品分类：
病毒纯化试剂盒
公司分类：
Virus_purification_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Storage Instruction:
- Store at 4°C in the dark.
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Datasheet:
Download
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Gene Information
- Entrez GeneID:
- 249
- Gene Name:
- ALPL
- Gene Alias:
- AP-TNAP,FLJ40094,FLJ93059,HOPS,MGC161443,MGC167935,TNAP,TNSALP
- Gene Description:
- alkaline phosphatase, liver/bone/kidney
- Omim ID:
- 146300, 171760, 241500, 241510
- Gene Ontology:
- Hyperlink
- Gene Summary:
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002971,OTTHUMP00000002972,alkaline phosphatase, tissue-nonspecific isozyme,alkaline phosphomonoesterase,glycerophosphatase,liver/bone/kidney-type alkaline phosphatase,tissue non-specific alkaline phosphatase,tissue-nonspecific ALP
- Gene Pathway
- Folate biosynthesis
- gamma-Hexachlorocyclohexane degradation
- Metabolic pathways
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Chondrocalcinosis
- Diabetes Complications
- Fractures, Bone
- Genetic Predisposition to Disease
- Hypertension
- Hypophosphatasia
- Kidney Failure, Chronic
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis
- Osteoporosis, Postmenopausal
- Spondylitis, Ankylosing
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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