Abnova/ETV6/NTRK3 DY易位FISH探针/1kit/FT0012
市场价：
¥0.00
美元价：
0.00
产品分类：
数字PCR系统
公司分类：
Digital_PCR_system
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Labeled FISH probes for identification of gene translocation using Fluoresecent In Situ Hybridization Technique. (Technology)
- Form:
- Liquid
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
- Storage Instruction:
- Store at 4°C in the dark.
- Note:
- Hybridization position of the probes on the chromosome.
- Probe 1:Size:Fluorophore:Location:
- ETV6Approximately 910kbTexas Red12p13
- Probe 2:Size:Fluorophore:Location:
- NTRK3Approximately 1,200kbFITC15q25
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Datasheet:
Download
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- ETV6
- NTRK3
- Gene Information
- Entrez GeneID:
- 2120
- Gene Name:
- ETV6
- Gene Alias:
- TEL,TEL/ABL
- Gene Description:
- ets variant 6
- Omim ID:
- 131440, 600618, 601626
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq
- Other Designations:
- TEL oncogene,TEL1 oncogene,ets variant gene 6 (TEL oncogene)
- Gene Information
- Entrez GeneID:
- 4916
- Gene Name:
- NTRK3
- Gene Alias:
- TRKC,gp145(trkC)
- Gene Description:
- neurotrophic tyrosine kinase, receptor, type 3
- Omim ID:
- 191316
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq
- Other Designations:
- ETS related protein-neurotrophic receptor tyrosine kinase fusion protein,ETV6-NTRK3 fusion,NT-3 growth factor receptor,OTTHUMP00000192915,neurotrophin 3 receptor,tyrosine kinase receptor C
品牌介绍
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