Abnova/BRAF/LMO7 Translocation FISH Probe/1kit/FT0034
市场价：
¥0.00
美元价：
0.00
产品分类：
CRISPR 细胞株
公司分类：
CRISPR_Cell_lines
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Labeled FISH probes for identification of gene translocation using Fluoresecent In Situ Hybridization Technique. (Technology)
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Storage Instruction:
- Store at 4°C in the dark.
- Note:
- Hybridization position of the probes on the chromosome.
- Probe 1:Size:Fluorophore:Location:
- BRAFApproximately 1050kbFITC7q34
- Probe 2:Size:Fluorophore:Location:
- LMO7Approximately 870kbTexas Red13q22.2
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulatory Status:
- For research use only (RUO)
- Datasheet:
Download
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- BRAF
- LMO7
- Gene Information
- Entrez GeneID:
- 673
- Gene Name:
- BRAF
- Gene Alias:
- B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1
- Gene Description:
- v-raf murine sarcoma viral oncogene homolog B1
- Omim ID:
- 115150, 164757, 211980
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq
- Other Designations:
- 94 kDa B-raf protein,B-Raf proto-oncogene serine/threonine-protein kinase (p94),Murine sarcoma viral (v-raf) oncogene homolog B1
- Gene Information
- Entrez GeneID:
- 4008
- Gene Name:
- LMO7
- Gene Alias:
- FBX20,FBXO20,KIAA0858,LOMP
- Gene Description:
- LIM domain 7
- Omim ID:
- 604362
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq
- Other Designations:
- F-box only protein 20,F-box protein Fbx20,LIM domain only 7,OTTHUMP00000018512,OTTHUMP00000040819,zinc-finger domain-containing protein
品牌介绍
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