Abnova/COL1A1裂鱼探头/1kit/FS0043
市场价：
¥0.00
美元价：
0.00
产品分类：
其他
公司分类：
Otherinstruments
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
- Form:
- Liquid
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
- Storage Instruction:
- Store at 4°C in the dark.
- Note:
- Hybridization position of the probes on the chromosome:
- Probe 1:Size:Fluorophore:Location:
- COL1A1Approximately 570kbTexas Red17q21.33
- Probe 2:Size:Fluorophore:Location:
- COL1A1Approximately 730kbFITC17q21.33
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Datasheet:
Download
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Gene Information
- Entrez GeneID:
- 1277
- Gene Name:
- COL1A1
- Gene Alias:
- OI4
- Gene Description:
- collagen, type I, alpha 1
- Omim ID:
- 114000, 120150, 130000, 130060, 166200, 166210, 166220, 166710, 259420
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
- Other Designations:
- alpha 1 type I collagen,collagen alpha 1 chain type I,collagen of skin, tendon and bone, alpha-1 chain,pro-alpha-1 collagen type 1,type I collagen alpha 1 chain
- Gene Pathway
- ECM-receptor interaction
- Focal adhesion
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aortic Aneurysm, Abdominal
- beta-Thalassemia
- Body Weight
- Bone Diseases
- Bone Diseases, Metabolic
- Bone Neoplasms
- Cardiovascular Diseases
- Chorioamnionitis
- Chronic Disease
- Clubfoot
- Colles" Fracture
- Connective Tissue Diseases
- Coronary Artery Disease
- Crohn Disease
- Crohn"s disease
- Cystic Fibrosis
- Cystic fibrosis
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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