Abnova/BCL6裂鱼探头/1kit/FS0068
市场价：
¥0.00
美元价：
0.00
产品分类：
蛋白纯化
公司分类：
Protein_purification
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
- Form:
- Liquid
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
- Storage Instruction:
- Store at 4°C in the dark.
- Probe 1:Size:Fluorophore:Location:
- BCL6Approximately 600kbTexas Red3q27.3
- Probe 2:Size:Fluorophore:Location:
- BCL6Approximately 740kbFITC3q27.3
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Probe Position:
- Datasheet:
Download
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Gene Information
- Entrez GeneID:
- 604
- Gene Name:
- BCL6
- Gene Alias:
- BCL5,BCL6A,LAZ3,ZBTB27,ZNF51
- Gene Description:
- B-cell CLL/lymphoma 6
- Omim ID:
- 109565
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- B-cell lymphoma 6 protein,B-cell lymphoma 6 protein transcript,cys-his2 zinc finger transcription factor,lymphoma-associated zinc finger gene on chromosome 3,zinc finger protein 51,zinc finger transcription factor BCL6S
- Related Disease
- Adenocarcinoma
- Central Nervous System Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hematologic Diseases
- HIV Infections
- Hodgkin Disease
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Lung Neoplasms
- Lymphoma, AIDS-Related
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Large-Cell, Diffuse
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Neovascularization, Pathologic
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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