Abnova/FGFR2/CEN10 CISH探头/1kit/CG0008
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美元价：
0.00
产品分类：
超声波清洗机
公司分类：
Ultrasonic_cleaning
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- FGFR2/CEN10 CISH Probe is designed for the qualitative detection of human FGFR2 gene amplifications as well as the detection of chromosome 10 alpha satellites in formalin-fixed, paraffin-embedded specimens by chromogenic in situ hybridization (CISH).
- Recommend Usage:
- The product is ready-to-use. No reconstitution, mixing, or dilution is required. Bring probe to room temperature (18-25°C) and mix briefly before use.
- Supplied Product:
- Reagent Provided:This Probe is composed of:1. Digoxigenin-labeled polynucleotides, which target sequences mapping in 10q26.12-10q26.13* (chr10:123,080,085-123,492,398) harboring the FGFR2 gene region.2. Dinitrophenyl-labeled polynucleotides, which target sequences mapping in 10p11.1-q11.1 specific for the alpha satellite centromeric region D10Z1 of chromosome 10. 3. Formamide based hybridization buffer.*according to Human Genome Assembly GRCh37/hg19
- Storage Instruction:
- Store at 2-8°C in an upright position. Return to storage conditions immediately after use.
- Note:
- The probe is intended to be used in combination with the CISH Implementation Kit 2 (Catalog #: KA5366), which provides necessary reagents for specimen pretreatment and post-hybridization processing.Interpretation of results:Using the CISH Implementation Kit 2 (Cat # KA5366), hybridization signals of Digoxigenin-labeled polynucleotides appear as dark green colored distinct dots (FGFR2 gene region), and Dinitrophenyl-labeled polynucleotides appear as bright red colored distinct dots (CEN 10).Normal situation: In interphases of normal cells or cells without an amplification involving the FGFR2 gene region, two distinct dot-shaped green and two distinct dot-shaped red signals appear.Aberrant situation: In cells with an amplification of the FGFR2 gene region, an increased number of green signals or green signal clusters will be observed.Overlapping signals may appear as brown signals. Other signal patterns than those described above may be observed in some abnormal samples. These unexpected signal patterns should be further investigated.
- Probe Position:
- Regulatory Status:
- For research use only (RUO)
- Interpretation of Result:
- Datasheet:
Download
- Applications
- Chromogenic In Situ Hybridization (FFPE Tissue)
- Breast carcinoma tissue section with FGFR2 (green) amplification.
- Application Image
- Chromogenic In Situ Hybridization (FFPE Tissue)
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品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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