Abnova/ACTB单克隆抗体,克隆AC-15/1kit/MAB8232
市场价:
¥0.00
美元价:
0.00
产品分类:
基因突变
公司分类:
Genetic_mutations
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of ACTB.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus amoino acids (Ac-DDDIAALVIDNGSGK) of human ACTB.
- Host:
- Mouse
- Theoretical MW (kDa):
- 42
- Reactivity:
- Human, Mouse, Rat
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Isotype:
- IgG1
- Recommend Usage:
- Western Blot (0.25-0.5 &mciro;g/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
- Storage Instruction:
- Store at -20°C on dry atmosphere.After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
- Download
- Publication Reference
- 1.
- AC133/CD133/Prominin-1.Shmelkov SV, St Clair R, Lyden D, Rafii S.Int J Biochem Cell Biol. 2005 Apr;37(4):715-9.
- 2.
- Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein.Corbeil D, Fargeas CA, Huttner WB.Biochem Biophys Res Commun. 2001 Jul 27;285(4):939-44.
- 3.
- The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions.Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt SM, Simmons PJ, Peault B, Buck DW, Huttner WB.J Biol Chem. 2000 Feb 25;275(8):5512-20.
- Applications
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining of rat skeletal muscle with ACTB monoclonal antibody, clone AC-15 (Cat # MAB8232).
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 60
- Gene Name:
- ACTB
- Gene Alias:
- PS1TP5BP1
- Gene Description:
- actin, beta
- Omim ID:
- 102630
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq
- Other Designations:
- PS1TP5-binding protein 1,actin, cytoplasmic 1,beta actin,beta cytoskeletal actin
- Gene Pathway
- Adherens junction
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Focal adhesion
- Hypertrophic cardiomyopathy (HCM)
- Leukocyte transendothelial migration
- Pathogenic Escherichia coli infection - EHEC
- Regulation of actin cytoskeleton
- Tight junction
- Vibrio cholerae infection
- Related Disease
- Breast cancer
- Breast Neoplasms
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品,重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体,可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体,我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案,为全人类的健康努力。
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