Abnova/IL12（人类）ELISpot试剂盒/1kit/KA3931
市场价：
¥0.00
美元价：
0.00
产品分类：
免疫组化试剂盒
公司分类：
Immunostain_SP_Kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- IL12 (Human) ELISpot Kit is a sandwich enzyme immunoassay for the quantitative measurement of Human IL12.
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Protocol:
Protocol Download
- Suitable Sample:
- Cell
- Sample Volume:
- 100 uL
- Label:
- Biotin-conjugated
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Datasheet:
- Download
- Applications
- Quantification
- Application Image
- Quantification
- IL12A
- IL12B
- Gene Information
- Entrez GeneID:
- 3592
- Gene Name:
- IL12A
- Gene Alias:
- CLMF,IL-12A,NFSK,NKSF1,P35
- Gene Description:
- interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- Omim ID:
- 161560
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq
- Other Designations:
- IL-12, subunit p35,NF cell stimulatory factor chain 1,cytotoxic lymphocyte maturation factor 1, p35,interleukin 12, p35,interleukin 12A,interleukin-12 alpha chain,natural killer cell stimulatory factor 1, 35 kD subunit
- Gene Information
- Entrez GeneID:
- 3593
- Gene Name:
- IL12B
- Gene Alias:
- CLMF,CLMF2,IL-12B,NKSF,NKSF2
- Gene Description:
- interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Omim ID:
- 161561, 177900, 209950, 600807
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq
- Other Designations:
- IL12, subunit p40,OTTHUMP00000160820,cytotoxic lymphocyte maturation factor 2, p40,interleukin 12, p40,interleukin 12B,interleukin-12 beta chain,natural killer cell stimulatory factor, 40 kD subunit,natural killer cell stimulatory factor-2
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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