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Abnova/EPOR monoclonal antibody (M01), clone 3D10/1kit/H00002057-M01
Abnova/EPOR monoclonal antibody (M01), clone 3D10/1kit/H00002057-M01
商品编号：
H00002057-M01
品牌：
abnovadx
市场价：
¥0.00
美元价：
0.00
产品分类：
基因突变
公司分类：
Genetic_mutations
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant EPOR.
- Immunogen:
- EPOR (NP_000112, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- PDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Datasheet:
- Download
- Publication Reference
- 1.
- GATA2 regulates the erythropoietin receptor in t(12;21) ALL.Gaine ME, Sharpe DJ, Smith JS, Colyer HAA, Hodges VM, Lappin TR, Mills KI.Oncotarget. 2017 Aug 2;8(39):66061-66074. doi: 10.18632/oncotarget.19792. eCollection 2017 Sep 12.
- Applications
- Western Blot (Cell lysate)
- EPOR monoclonal antibody (M01), clone 3D10. Western Blot analysis of EPOR expression in HeLa.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of EPOR expression in transfected 293T cell line by EPOR monoclonal antibody (M01), clone 3D10.Lane 1: EPOR transfected lysate (Predicted MW: 55.1 KDa).Lane 2: Non-transfected lysate.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of EPOR transfected lysate using anti-EPOR monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EPOR MaxPab rabbit polyclonal antibody.
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged EPOR is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- ELISA
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Western Blot (Transfected lysate)
- enlarge
- Western Blot (Recombinant protein)
- Immunoprecipitation
- enlarge
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Gene Information
- Entrez GeneID:
- 2057
- GeneBank Accession#:
- NM_000121
- Protein Accession#:
- NP_000112
- Gene Name:
- EPOR
- Gene Alias:
- MGC138358
- Gene Description:
- erythropoietin receptor
- Omim ID:
- 133100, 133171
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq
- Other Designations:
- -
- Gene Pathway
- Cytokine-cytokine receptor interaction
- Hematopoietic cell lineage
- Jak-STAT signaling pathway
- Related Disease
- Genetic Predisposition to Disease
- Lymphoproliferative Disorders
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
- Polycythemia Vera
- Thrombocythemia, Hemorrhagic
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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