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Abnova/Amyloid beta 4-10 recombinant monoclonal antibody, clone WO2/1kit/RAB00070
Abnova/Amyloid beta 4-10 recombinant monoclonal antibody, clone WO2/1kit/RAB00070
市场价：
¥0.00
美元价：
0.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Recombinant mouse monoclonal antibody raised against human Amyloid beta 4-10.
- Immunogen:
- Original antibody is raised against a synthetic peptide of human Amyloid beta.
- Reactivity:
- Human
- Specificity:
- This antibody recognizes acid residues 4-10 of human Amyloid beta.
- Form:
- Liquid
- Purification:
- Protein A affinity purification
- Isotype:
- IgG2a, kappa
- Recommend Usage:
- ELISA (0.1 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)Western Blot (1 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.2 (0.02% Proclin 300).
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Antibody Species:
- Mouse
- Datasheet:
Download
- Applications
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Enzyme-linked Immunoabsorbent Assay
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Enzyme-linked Immunoabsorbent Assay
- Gene Information
- Entrez GeneID:
- 351
- Protein Accession#:
- P05067
- Gene Name:
- APP
- Gene Alias:
- AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2
- Gene Description:
- amyloid beta (A4) precursor protein
- Omim ID:
- 104760, 605714
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide,peptidase nexin-II,protease nexin-II
- Interactome
- Gene Pathway
- Alzheimer"s disease
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis, Familial
- Cardiovascular Diseases
- Celiac Disease
- Cerebral Hemorrhage
- Cerebrovascular Disorders
- Cognition
- Cognition Disorders
- Dementia
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Down Syndrome
- Edema
- Genetic Predisposition to Disease
- Headache
- Macular Degeneration
- Mental Status Schedule
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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