Abnova/ABCB1重组单克隆抗体，克隆MRK16/1kit/RAB0018
市场价：
¥0.00
美元价：
0.00
产品分类：
荧光计
公司分类：
Fluorometry
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Recombinant mouse monoclonal antibody raised against human ABCB1.
- Immunogen:
- Original antibody is raised against drug resistant K-562 cells.
- Reactivity:
- Human
- Specificity:
- This antibody recognizes a discontinuous extracellular epitope on human ABCB1.
- Form:
- Liquid
- Purification:
- Protein A affinity purification
- Isotype:
- IgG1, kappa
- Recommend Usage:
- Flow Cytometry (1 ug/mL)ImmunofluorescenceImmunoprecipitation (10 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.2 (0.02% Proclin 300).
- Storage Instruction:
- Store at 4°C for up to 3 months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Antibody Species:
- Mouse
- Datasheet:
Download
- Applications
- Immunofluorescence
- Immunoprecipitation
- Flow Cytometry
- Application Image
- Immunofluorescence
- Immunoprecipitation
- Flow Cytometry
- Gene Information
- Entrez GeneID:
- 5243
- Protein Accession#:
- P08183
- Gene Name:
- ABCB1
- Gene Alias:
- ABC20,CD243,CLCS,GP170,MDR1,MGC163296,P-GP,PGY1
- Gene Description:
- ATP-binding cassette, sub-family B (MDR/TAP), member 1
- Omim ID:
- 171050
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq
- Other Designations:
- ATP-binding cassette, subfamily B, member 1,P glycoprotein 1,P-glycoprotein 1,colchicin sensitivity,doxorubicin resistance,multidrug resistance 1,multidrug resistance protein 1
- Gene Pathway
- ABC transporters
- Related Disease
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Addison Disease
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amnesia
- Anemia
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Attention Deficit Disorder with Hyperactivity
- Bipolar Disorder
- Birth Weight
- Body Weight
- Brain Neoplasms
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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