Abnova/ADRB2（磷酸化S261）多克隆抗体/1kit/PAB8156
市场价：
¥0.00
美元价：
0.00
产品分类：
转录表达
公司分类：
Target_Expression
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ADRB2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S261 of human ADRB2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)Dot Blot (1:500)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Publication Reference
- 1.
- Association between a beta2-adrenergic receptor polymorphism and elite endurance performance.Wolfarth B, Rankinen T, Muhlbauer S, Scherr J, Boulay MR, Perusse L, Rauramaa R, Bouchard C.Metabolism. 2007 Dec;56(12):1649-51.
- 2.
- High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC.Science. 2007 Nov 23;318(5854):1258-65. Epub 2007 Oct 25.
- Applications
- Enzyme-linked Immunoabsorbent Assay
- Dot Blot (Peptide)
- Dot blot analysis of ADRB2 (phospho S261) polyclonal antibody (Cat # PAB8156) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 ug/mL.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Dot Blot (Peptide)
- enlarge
- Gene Information
- Entrez GeneID:
- 154
- Protein Accession#:
- P07550;NP_000015
- Gene Name:
- ADRB2
- Gene Alias:
- ADRB2R,ADRBR,B2AR,BAR,BETA2AR
- Gene Description:
- adrenergic, beta-2-, receptor, surface
- Omim ID:
- 109690, 600807, 601665
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq
- Other Designations:
- beta-2 adrenergic receptor,beta-2 adrenoceptor,catecholamine receptor
- Gene Pathway
- Calcium signaling pathway
- Endocytosis
- Neuroactive ligand-receptor interaction
- Related Disease
- Acanthosis Nigricans
- Acromegaly
- Acute Disease
- Albuminuria
- Altitude Sickness
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anemia, Sickle Cell
- Anemia, sickle cell
- Angina, Unstable
- Anorexia Nervosa
- Arteriosclerosis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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