Abnova/ADD1 (phospho S726) polyclonal antibody/1kit/PAB25323
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆试剂盒
公司分类：
Cloning_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ADD1.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S726 of human ADD1.
- Sequence:
- T-P-Sp-F-L
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Affinity purification
- Recommend Usage:
- Western Blot (1:500-1:1000)Immunohistochemistry (1:50-100)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extract from HT-29 cells untreated or treated with Doxorubicin (1 mM, 30 min), using ADD1 (phospho S726) polyclonal antibody (Cat # PAB25323).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using ADD1 (phospho S726) polyclonal antibody (Cat # PAB25323).
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 118
- Protein Accession#:
- P35611
- Gene Name:
- ADD1
- Gene Alias:
- ADDA,MGC3339,MGC44427
- Gene Description:
- adducin 1 (alpha)
- Omim ID:
- 102680, 145500
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000151164,OTTHUMP00000151165,erythrocyte adducin alpha subunit
- Related Disease
- Albuminuria
- Alcoholism
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Arterial Occlusive Diseases
- Arteriosclerosis
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cerebral Hemorrhage
- Cerebral Palsy
- Cerebrovascular Accident
- Cerebrovascular Disorders
- Cognition Disorders
- Constriction, Pathologic
- Coronary Artery Disease
- Coronary Disease
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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