Abnova/ADAM17 (phospho T735) polyclonal antibody/1kit/PAB31643
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆试剂盒
公司分类：
Cloning_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of human ADAM17 (phospho T735).
- Immunogen:
- A synthetic peptide corresponding to amino acids 670-750 of human ADAM17 (phospho T735).
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody detects endogenous levels of ADAM17 protein only when phosphorylated at T735.
- Form:
- Liquid
- Purification:
- Affinity purification
- Isotype:
- IgG
- Recommend Usage:
- ELISA (1:20000)Immunohistochemistry (1:100-300)Western Blot (1:500-2000)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (50% glycerol, 0.5% BSA and 0.02% sodium azide).
- Storage Instruction:
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot
- Immunohistochemistry
- Enzyme-linked Immunoabsorbent Assay
- Application Image
- Western Blot
- Immunohistochemistry
- Enzyme-linked Immunoabsorbent Assay
- Gene Information
- Entrez GeneID:
- 6868
- Protein Accession#:
- P78536
- Gene Name:
- ADAM17
- Gene Alias:
- CD156b,MGC71942,TACE,cSVP
- Gene Description:
- ADAM metallopeptidase domain 17
- Omim ID:
- 603639
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq
- Other Designations:
- TNF-alpha converting enzyme,a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme),snake venom-like protease,tumor necrosis factor, alpha, converting enzyme
- Interactome
- Gene Pathway
- Alzheimer"s disease
- Epithelial cell signaling in Helicobacter pylori infection
- Notch signaling pathway
- Related Disease
- Alzheimer Disease
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Coronary Artery Disease
- Crohn Disease
- Crohn"s disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Lymphoma, Non-Hodgkin
- Myocardial Infarction
- Peripheral Vascular Diseases
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
联络我们
