Abnova/AAK1 polyclonal antibody/1kit/PAB16581
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆试剂盒
公司分类：
Cloning_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of AAK1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 20 amino acids of human AAK1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Recommend Usage:
- Western Blot (1-2 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Publication Reference
- 1.
- A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.Henderson DM, Conner SD.Mol Biol Cell. 2007 Jul;18(7):2698-706. Epub 2007 May 9.
- 2.
- The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton.Smythe E, Ayscough KR.EMBO Rep. 2003 Mar;4(3):246-51.
- 3.
- Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis.Conner SD, Schmid SL.J Cell Biol. 2002 Mar 4;156(5):921-9. Epub 2002 Mar 4.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of AAK1 in A-20 cell lysate with AAK1 polyclonal antibody (Cat # PAB16581) at (A) 1 and (B) 2 ug/mL .
- Immunocytochemistry
- Immunocytochemistry of AAK1 in A-20 cells with AAK1 polyclonal antibody (Cat # PAB16581) at 5 ug/mL .
- Enzyme-linked Immunoabsorbent Assay
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunocytochemistry
- enlarge
- Enzyme-linked Immunoabsorbent Assay
- Gene Information
- Entrez GeneID:
- 22848
- Protein Accession#:
- NP_055726
- Gene Name:
- AAK1
- Gene Alias:
- DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
- Gene Description:
- AP2 associated kinase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- adaptor-associated kinase 1
- Related Disease
- Parkinson Disease
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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