Abnova/AAK1 polyclonal antibody/1kit/PAB16579
市场价：
¥0.00
美元价：
0.00
产品分类：
基因突变
公司分类：
Genetic_mutations
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of AAK1.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 18 amino acids of human AAK1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Recommend Usage:
- Western Blot (1-2 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Publication Reference
- 1.
- A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.Henderson DM, Conner SD.Mol Biol Cell. 2007 Jul;18(7):2698-706. Epub 2007 May 9.
- 2.
- The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton.Smythe E, Ayscough KR.EMBO Rep. 2003 Mar;4(3):246-51.
- 3.
- Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis.Conner SD, Schmid SL.J Cell Biol. 2002 Mar 4;156(5):921-9. Epub 2002 Mar 4.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of AAK1 in A-20 cell lysate with AAK1 polyclonal antibody (Cat # PAB16579) at (A) 1 and (B) 2 ug/mL .
- Enzyme-linked Immunoabsorbent Assay
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Enzyme-linked Immunoabsorbent Assay
- Gene Information
- Entrez GeneID:
- 22848
- Protein Accession#:
- NP_055726
- Gene Name:
- AAK1
- Gene Alias:
- DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
- Gene Description:
- AP2 associated kinase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- adaptor-associated kinase 1
- Related Disease
- Parkinson Disease
- Tobacco Use Disorder
品牌介绍
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