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当前位置: 首页 > 产品中心 > Genetic_mutations > Abnova/8-OHdG单克隆抗体,克隆N45.1/1kit/MAB6116
商品详细Abnova/8-OHdG单克隆抗体,克隆N45.1/1kit/MAB6116
Abnova/8-OHdG单克隆抗体,克隆N45.1/1kit/MAB6116
Abnova/8-OHdG单克隆抗体,克隆N45.1/1kit/MAB6116
商品编号: MAB6116
品牌: abnovadx
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 基因突变
公司分类: Genetic_mutations
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against 8-OHdG.
  • Immunogen:
  • 8-OHdG conjugated with KLH.
  • Host:
  • Mouse
  • Specificity:
  • 8-sulfhydrylguanosine and 8-OHG demonstrate some cross-reactivity at high concentrations (at least 2 orders of magnitude were required for positive cross-reactivity).
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (1-10 ug/mL)The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 50 mM TBS (1% BSA)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.After reconstitution with deionized water, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.
  • Datasheet:
  • PDF DownloadDownload
  • Publication Reference
  • 1.
  • SUMO2 regulates vascular endothelial function and oxidative stress in mice.Kim YR, Jacobs JS, Li Q, Gaddam RR, Vikram A, Liu J, Kassan M, Irani K, Kumar S.Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1292-H1300. doi: 10.1152/ajpheart.00530.2019. Epub 2019 Oct 4.
  • 2.
  • Protection against pyrimidine dimers, p53, and 8-hydroxy-2"-deoxyguanosine expression in ultraviolet-irradiated human skin by sunscreens: difference between UVB + UVA and UVB alone sunscreens.Liardet S, Scaletta C, Panizzon R, Hohlfeld P, Laurent-Applegate L.J Invest Dermatol. 2001 Dec;117(6):1437-41.
  • 3.
  • Formation of 8-hydroxy-2"-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in rat liver after ischemia-reperfusion: distinct localization of the two oxidatively modified products.Yamagami K, Yamamoto Y, Kume M, Ishikawa Y, Yamaoka Y, Hiai H, Toyokuni S.Antioxid Redox Signal. 2000 Spring;2(1):127-36.
  • 4.
  • Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats.Nakae D, Akai H, Kishida H, Kusuoka O, Tsutsumi M, Konishi Y.Lab Invest. 2000 Feb;80(2):249-61.
  • 5.
  • Intranuclear distribution of 8-hydroxy-2"-deoxyguanosine. An immunocytochemical study.Toyokuni S, Iwasa Y, Kondo S, Tanaka T, Ochi H, Hiai H.J Histochem Cytochem. 1999 Jun;47(6):833-6.
  • 6.
  • Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.Ihara Y, Toyokuni S, Uchida K, Odaka H, Tanaka T, Ikeda H, Hiai H, Seino Y, Yamada Y.Diabetes. 1999 Apr;48(4):927-32.
  • Applications
  • Immunohistochemistry
  • Application Image
  • Immunohistochemistry
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品,重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体,可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体,我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案,为全人类的健康努力。