Abnova/Asgr1单克隆抗体，克隆8D7/1kit/MAB5646
市场价：
¥0.00
美元价：
0.00
产品分类：
克隆基因
公司分类：
Cloned_Genes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native Asgr1.
- Immunogen:
- Native purified rat liver membrane extracts Asgr1.
- Host:
- Mouse
- Reactivity:
- Human, Rat
- Specificity:
- The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 KDa) which mediates binding, internalisation and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i.e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope on RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
- Form:
- Liquid
- Isotype:
- IgG1
- Recommend Usage:
- Recommend dilution at 1:10The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.1% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Publication Reference
- 1.
- A monoclonal antibody to rat asialoglycoprotein receptor that recognizes an epitope specific to its major subunit.Shimada M, Mizuno M, Uesu T, Nasu J, Okada H, Shimomura H, Yamamoto K, Tsuji T, Shiratori Y.Hepatol Res. 2003 May;26(1):55-60.
- 2.
- Distribution of asialoglycoprotein receptor in human hepatocellular carcinoma.Hyodo I, Mizuno M, Yamada G, Tsuji T.Liver. 1993 Apr;13(2):80-5.
- 3.
- Monoclonal antibodies identifying antigens on distinct domains of rat hepatocytes.Mizuno M, Yamada G, Sugiyama T, Vierling JM, Brown WR.Liver. 1987 Oct;7(5):251-9.
- Applications
- Western Blot
- Immunohistochemistry (Frozen sections)
- Enzyme-linked Immunoabsorbent Assay
- Flow Cytometry
- Application Image
- Western Blot
- Immunohistochemistry (Frozen sections)
- Enzyme-linked Immunoabsorbent Assay
- Flow Cytometry
- Gene Information
- Entrez GeneID:
- 24210
- Gene Name:
- Asgr1
- Gene Alias:
- ASGR,MGC108731,RATRHL1,RHL1
- Gene Description:
- asialoglycoprotein receptor 1
- Gene Ontology:
- Hyperlink
- Other Designations:
- Asialoglycoprotein receptor 1 (hepatic lectin),asialoglycoprotein receptor (RHL1),asialoglycoprotein receptor 1 (hepatic lectin),hepatic lectin 1 RHL1,hepatic lectin 1, RHL1
品牌介绍
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