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Abnova/ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270/1kit/MAB14918
Abnova/ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270/1kit/MAB14918
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产品分类：
转录表达
公司分类：
Target_Expression
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against synthetic phosphopeptide of human ACACA/ACACB.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding S79 of human ACACA/ACACB.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Isotype:
- IgG
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2000)Western Blotting (1:1000-1:5000)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
- Storage Instruction:
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Western Blot (Cell lysate)
- Western Blot analysis of A431 cell lysate Lane 1: nontreated and Lane 2: treated with Lambda Protein Phosphatase with ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270 (Cat # MAB14918).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270 (Cat # MAB14918).
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ACACA
- ACACB
- Gene Information
- Entrez GeneID:
- 31
- Protein Accession#:
- Q13085;O00763
- Gene Name:
- ACACA
- Gene Alias:
- ACAC,ACC,ACC1,ACCA
- Gene Description:
- acetyl-Coenzyme A carboxylase alpha
- Omim ID:
- 200350
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5" sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- ACC-alpha,OTTHUMP00000164069,acetyl-CoA carboxylase 1,acetyl-CoA carboxylase-alpha
- Gene Information
- Entrez GeneID:
- 32
- Protein Accession#:
- Q13085;O00763
- Gene Name:
- ACACB
- Gene Alias:
- ACC2,ACCB,HACC275
- Gene Description:
- acetyl-Coenzyme A carboxylase beta
- Omim ID:
- 601557
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria.ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis.There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq
- Other Designations:
- acetyl-CoA carboxylase 2
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