当前位置：
首页
>
产品中心 >
Genetic_mutations >
Abnova/AADAC monoclonal antibody (M01), clone 2E8/1kit/H00000013-M01
Abnova/AADAC monoclonal antibody (M01), clone 2E8/1kit/H00000013-M01
商品编号：
H00000013-M01
品牌：
abnovadx
市场价：
¥0.00
美元价：
0.00
产品分类：
基因突变
公司分类：
Genetic_mutations
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant AADAC.
- Immunogen:
- AADAC (NP_001077, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- QLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFINWSSLLPERFIKGHVYNNP
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Interspecies Antigen Sequence:
- Mouse (73); Rat (69)
- Datasheet:
- Download
- Publication Reference
- 1.
- N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity.Muta K, Fukami T, Nakajima M, Yokoi TBiochem Pharmacol. 2013 Oct 11. pii: S0006-2952(13)00651-5. doi: 10.1016/j.bcp.2013.10.001.
- 2.
- Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia.Kobayashi Y, Fukami T, Higuchi R, Nakajima M, Yokoi T.Biochem Pharmacol. 2012 Aug 23.
- 3.
- A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Diminished Enzyme Activity.Shimizu M, Fukami T, Kobayashi Y, Takamiya M, Aoki Y, Nakajima M, Yokoi T.Drug Metab Dispos. 2012 Mar 13. [Epub ahead of print]
- 4.
- Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse.Kobayashi Y, Fukami T, Nakajima A, Watanabe A, Nakajima M, Yokoi T.Drug Metab Dispos. 2012 Apr;40(4):671-9. Epub 2011 Dec 29.
- 5.
- Human Arylacetamide Deacetylase Is A Principal Enzyme in Flutamide Hydrolysis.Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T.Drug Metab Dispos. 2009 Jul;37(7):1513-20. Epub 2009 Apr 1.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged AADAC is approximately 3ng/ml as a capture antibody.
- Protocol Download
- ELISA
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Gene Information
- Entrez GeneID:
- 13
- GeneBank Accession#:
- NM_001086
- Protein Accession#:
- NP_001077
- Gene Name:
- AADAC
- Gene Alias:
- CES5A1,DAC
- Gene Description:
- arylacetamide deacetylase (esterase)
- Omim ID:
- 600338
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq
- Other Designations:
- arylacetamide deacetylase
- Gene Pathway
- Tropane, piperidine and pyridine alkaloid biosynthesis
- Related Disease
- Tobacco Use Disorder
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
联络我们
