当前位置：
首页
>
产品中心 >
Two_Hybrid_Systems >
Abnova/A2M monoclonal antibody (M03), clone 2B5/1kit/H00000002-M03
Abnova/A2M monoclonal antibody (M03), clone 2B5/1kit/H00000002-M03
商品编号：
H00000002-M03
品牌：
abnovadx
市场价：
¥0.00
美元价：
0.00
产品分类：
双杂交系统
公司分类：
Two_Hybrid_Systems
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant A2M.
- Immunogen:
- A2M (NP_000005.2, 641 a.a. ~ 730 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTET
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Interspecies Antigen Sequence:
- Mouse (62); Rat (63)
- Datasheet:
- Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged A2M is 3 ng/ml as a capture antibody.
- Protocol Download
- ELISA
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between IL1B and A2M. HeLa cells were stained with anti-IL1B rabbit purified polyclonal 1:1200 and anti-A2M mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- In situ Proximity Ligation Assay (Cell)
- enlarge
- Gene Information
- Entrez GeneID:
- 2
- GeneBank Accession#:
- NM_000014
- Protein Accession#:
- NP_000005.2
- Gene Name:
- A2M
- Gene Alias:
- CPAMD5,DKFZp779B086,FWP007,S863-7
- Gene Description:
- alpha-2-macroglobulin
- Omim ID:
- 103950, 104300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
- Other Designations:
- -
- Interactome
- Gene Pathway
- Complement and coagulation cascades
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Cognition Disorders
- Dementia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Diseases in Twins
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Kidney Failure, Chronic
- Liver Cirrhosis
- Macular Degeneration
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
联络我们
