Abnova/A2M (Human) Native Protein/1kit/P4913
市场价：
¥0.00
美元价：
0.00
产品分类：
其它天然蛋白
公司分类：
Other_natural_proteins
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
- Specification
- Product Description:
- Human A2M native protein from human blood.
- Host:
- Human
- Theoretical MW (kDa):
- 725
- Form:
- Lyophilized
- Preparation Method:
- Native protein purified from human blood
- Purification:
- Saltprecipitation/Chelate Chromatography/Gelfiltration
- Concentration:
- 2-4 mg/mL
- Purity:
- > 90% by SDS-PAGE
- Storage Buffer:
- Lyophilized from 50 mM phosphate buffer, 100 mM NaCl, 500 ug glycine, pH 7.4
- Storage Instruction:
- Store at -80°C.After reconstitution with deionized water, store at -80°C.Aliquot to avoid repeated freezing and thawing.
- Note:
- Do not use alpha-2-Macroglobulin in presence of DTT, even at 1 mM DTT causes reversible dissociation into inactive subunits.It is sensitive to acidic pH and denatured below pH 4.0. Ammonia methylamine and hydroxylamine (above pH 7.0) cause irreversible conversion to the inactive form.
- Datasheet:
Download
- Applications
- SDS-PAGE
- Application Image
- SDS-PAGE
- Gene Information
- Entrez GeneID:
- 2
- Gene Name:
- A2M
- Gene Alias:
- CPAMD5,DKFZp779B086,FWP007,S863-7
- Gene Description:
- alpha-2-macroglobulin
- Omim ID:
- 103950, 104300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
- Other Designations:
- -
- Interactome
- Gene Pathway
- Complement and coagulation cascades
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Cognition Disorders
- Dementia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Diseases in Twins
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Kidney Failure, Chronic
- Liver Cirrhosis
- Macular Degeneration
品牌介绍
Abnova是世界上最大的抗体制造商。亚诺法的所有产品，重组蛋白和抗体都是利用最新的技术及由SPF等级动物实验室制造生产出来。我们的目标是生产人类基因组内每个基因至少要有一个相对应的抗体，可以提供给来自于学术机构、行业的伙伴和合作者做研究。亚诺法有许多多样化的单克隆及多克隆抗体，我们更进一步开发一系列的整合系统与相关应用包含配对抗体、ELISA试剂盒与荧光原位杂交(FISH)探针。这些工具对生物标记开发与转译研究都是必须的。亚诺法亦有针对糖尿病、传染疾病与癌症的体外检验试剂专案以及用于治疗败血症的全人类抗体药技专案，为全人类的健康努力。
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